Event - Genomic Disorders 2013: From 60 years of DNA to human genomes in the clinic

What

The 7th Wellcome Trust Genomic Disorders conference will present an exciting blend of genomic science and clinical medicine. This meeting aims to bring together scientists and clinicians interested in genomic variation in humans and the mechanisms by which it exerts its phenotypic effects.

Genomic Disorders 2013 will discuss the latest findings relating to the genomic basis of rare disorders as these can provide such powerful insights into human biology. Genome-wide analyses, including array Comparative Genomic Hybridization (aCGH) and Whole Exome Sequencing (WES), are proving to be of great value in discovering the genetic basis of rare disorders and illustrate the heuristic power of humans as a model organism. A particular focus of this meeting will be on bioinformatics approaches used to interpret genomic variants and on therapeutic targets for rare genetic diseases.

Please note that due to building works to expand the Wellcome Trust Conference Centre at Hinxton, Genomic Disorders 2013 will take place at Homerton College - part of the historic University of Cambridge.

Scientific sessions will include:

Natural variation
Developmental genetics
Animal models of rare disorders
Interpretation of genomic variants
Therapeutics

Special events

This year’s meeting coincides with the 60th anniversary of the discovery of the structure of DNA by Watson and Crick in Cambridge in April 1953. To commemorate this, the meeting will include an exhibition/talk about some of the Cambridge sites connected with this remarkable discovery, which laid the foundation for genomic science.

Scientific organisers
Han Brunner Radboud University Nijmegen Medical Centre, The Netherlands
Helen Firth Cambridge University Dept. of Medical Genetics, UK
Matthew Hurles Wellcome Trust Sanger Institute, UK
Jim Lupski Baylor College of Medicine, USA

Invited speakers:

Les Biesecker NIH, USA
Ewan Birney EMBL-EBI, UK
Sydney Brenner Howard Hughes Medical Institute, USA
Johan den Dunnen Leiden University Medical Center, The Netherlands
Santhosh Girirajan Pennsylvania State University, USA
Robert C. Green Brigham and Women's Hospital and Harvard Medical School, USA
Tamar R. Grossman ISIS Pharmaceuticals, USA
Monica Justice Baylor College of Medicine, USA
Nico Katsanis Duke University, USA
John Mattick Garvan Institute of Medical Research, Australia
Serena Nik-Zainal Wellcome Trust Sanger Institute, UK
Wolf Reik Babraham Institute, UK
Renata Salecl University of Ljubljana, Slovenia
Nicole Soranzo Wellcome Trust Sanger Institute, UK
James Watson Cold Spring Harbor Laboratories, USA
Brunhilde Wirth University of Cologne, Germany

Abstracts from all areas of genomic medicine are welcome, several talks will be selected from submitted abstracts.

Programme:

The conference website will be updated with the programme when it becomes available so please check the site for updates.
The conference will open with registration from 15:00 on the 10 April with talks starting at 17:00. The conference will close at approx. 17:00 on 12 April.