MLPA Validation

Introduction

Summary about MLPA validation

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MLPA validation summary

Presentation: Multiplex Ligation-dependent Probe Amplification (MLPA) - The interlaboratory collaborative study ?

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Brussels meeting-03-2006.pdf

Questionnaires

Identification of the variability of procedures in the use of MLPA kits for the identification of copy number changes

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Download:	Questionnaire-MLPAprocedure-validation.doc

Towards diagnostic validation of MLPA: questionnaire on the MLPA tests performed in laboratories and the ability to share samples with deletions or copy numbers changes

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Download:	MLPAQuestionnaire-positive controls.doc

Procedures for technical evaluation of MLPA, using the "BRCA1 validation kit" and corresponding files to report the data

Run 1 & 2: negative control samples

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Download procedure:	Procedure-BRCA1-Validation kit.doc
Download report:	Data_Report_BRCA1_ValidationKit.xls

Run 3 & 4: clinical samples

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Download procedure:	Procedure_BRCA1_validationkit_run3-4.doc
Download report:	Data_Report_BRCA1_validationkit_run3-4.xls

Evaluation of performance of the existing IT tools for MLPA data analysis

Procedure

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Download procedure:	Procedure_normalisation_DMD_MLPA89files.doc
Download report:	Report_results_MLPA_normalisation_89DMDtraces.xls

DMD Folders

DMD Folders

DMD-P034-1 DMD-P035-2 DMD-P034-3 DMD-P035-4 DMD-P034-5 DMD-P035-6 Download all files at once

Results

Run 1 & 2: negative control samples + evaluation of IT tools: preliminary results

Download as word doc:

MLPA_validation_neg_contr_prelim_results.doc

Last changed: 2008-10-15

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